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Stimulation of whiskers of a rat lead to localized changes in hemodynamics enabling high resolution functional mapping of the brain.

Medical Optics

Prof. Dr. Turgut Durduran

    Activities:


ICFO-Medical Optics (ICFO-MEDOPT) group was founded in 2009 by Dr Turgut Durduran as an inter-disciplinary group that develops new technologies using advanced photonics for pre-clinical and clinical bio-medicine.

The group’s main expertise is in diffuse optical monitoring and tomography which uses photon diffusion to probe “deep” (0.1-10cm) into tissues. Our research aims to advance the field in theoretical instrumentation and application oriented approaches in parallel. We focus on applications in neurology and oncology and in both pre-clinical animal model studies and in clinical human studies.

Inter-disciplinary, collaborative work forms the core of our vision and we routinely work with biomedical centers, hospitals and engineering departments in Spain, around Europe and abroad. In particular, we have strong ties with other centers in Barcelona area and with researchers at the University of Pennsylvania, USA.

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Medical Optics

Prof. Dr. Turgut Durduran

    Former Group Members
  • Juan Aguirre, Postdoctoral researcher
  • Rubén Benet, Research engineer
  • Igor Blanco, PhD student
  • Edén Corrales, Research engineer
  • Gianluca Cotta, Research engineer
  • Parisa Farzam, PhD student
  • Alexia Giannoula, Postdoctoral researcher
  • Joseph Lee Hollmann, Postdoctoral researcher
  • Johannes Johansson, Research fellow
  • Anna Kristine Kristoffersen, Postdoctoral researcher
  • Claus Lindner, PhD student
  • Taisuke Minagawa, Postdoctoral researcher
  • Néstor Hugo Oliverio, Research engineer
  • Francisco Remiro, Research engineer
  • Kristian Sexton, Postdoctoral researcher
  • Efraín Solarte, Visiting professor
  • Mehmet Ali Süzen, Postdoctoral researcher
  • Claudia Patricia Valdés, PhD student
  • Hari Maliakal Madhom Varma, Research fellow
  • Udo Michael Weigel, Research fellow
  • Peyman Zirak, Research fellow

Medical Optics

Prof. Dr. Turgut Durduran

    Invited Talks
  • Non-invasive, diffuse optical techniques for functional imaging T. Durduran VIII Spanish Drug Discovery Network Meeting 2016, volume Invited talk. SLAS Europe, November 2016
  • Non-invasive, diffuse optical techniques for functional imaging T. Durduran VIII Spanish Drug Discovery Network Meeting 2016, SLAS Europe, November 2016
  • Hybrid near-infrared diffuse optical methods for bed-side cerebral monitoring T. Durduran XVII Simposium Internacional de Neuromonitorizacion y Tratamiento Del Paciente Neurocritico (PIC 2016), Barcelona, November 2016.
  • Measuring cerebral blood flow with diffuse correlation spectroscopy J. Hollmann, T. Durduran 3rd European autumn school on cerebral oxymetry and optical imaging. University of Picardie, Amiens, November 2016.
  • Non-invasive, diffuse optical techniques for functional imaging T. Durduran VIII Spanish Drug Discovery Network Meeting 2016, SLAS Europe, November 2016
  • 'Why is my hand red?' or the tales of diffuse light in tissues T. Durduran Jornadas de Estudiantes en Ingenieria Biomedica, IEEE EMBS BCN Student Club, July 2016
  • Using diffuse light and speckle statistics to non-invasively measure blood flow; from theoretical foundations to clinical applications T. Durduran International School on Light Sciences and Technologies, Universidad Internacional Menendez Pelayo, Madrid, June 2016
  • Using light to probe inside the body T. Durduran Pint of Science Festival 2016, Barcelona, May 2016
  • Development and applications of diffuse correlation spectroscopy for non-invasive measurement of blood flow in clinics T. Durduran Optical Tomography and Spectroscopy 2016, Fort Lauderdale, Florida United States, April 2016
  • Cerebral metabolism and blood flow during bispectral index-controlled, propofol-induced anesthesia assessed by hybrid diffuse optics C. Lindner, I. Chochrón da Prat, Á. Sánchez-Guerrero, U. M. Weigel, M. de Nadal, J. Sahuquillo, D. Turgut OSA Biomedicals Topicals, Optical Society of America, 2016
  • High density speckle contrast optical tomography for transcranial, three-dimensional imaging of cerebral blood flow in rodents J. Hollmann, T. Dragojevi?, H. M. Varma, C. Justicia, C. Valdes, J. P. Culver, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
  • How can you see inside my body with light? T. Durduran 4th Symposium of Update in Dialysis, Hospital Clinic Barcelona, April 2016
  • Hybrid near-infrared diffuse optical methods for bed-side cerebral monitoring T. Durduran 9th International Update on Neuro-Anesthesia & Neuro-intensive care, Hospital Clinic Barcelona, April 2016
  • Hybrid near-infrared diffuse optical methods for bed-side cerebral monitoring T. Durduran 9th International Update on Neuro-Anesthesia & Neuro-intensive Care, Barcelona, April 2016
    Talks
  • Photonics advancements in time-domain diffuse imaging: Towards hand-held and wearable devices A. Pifferi, A. Dalla Mora, E. Martinenghi, D. Contini, L. di Sieno, R. Re, S. Arridge, F. Martelli, A. Tosi, A. Farina, T. Durduran,. A. Torricelli Optical Tomography and Spectroscopy 2016, Fort Lauderdale, Florida United States, April 2016
  • Neuromonitoring and imaging of cerebral blood flow with diffuse correlation spectroscopy T. Durduran University of Picardie Jules Verne and the Faculty of Medecine, November 2016
  • Neuromonitoring and imaging of cerebral blood flow with diffuse correlation spectroscopy T. Durduran 4th European autumn school on cerebral oxymetry and optical imaging. University of Picardie, Amiens, November 2016
  • Compact eight channel time-domain diffuse optical tomography system based on SiPMs for functional brain imaging S. Tagliabue, L. Di Sieno, A. Dalla Mora, E. Martinenghi, A. Farina, D. Turgut, A. Torricelli, A. Pifferi fNIRS 2016, Paris, France, October 2016
  • Concurrent diffuse optical measurement of cerebral hemodynamics and EEG during transcranial direct current stimulation (tDCS) in humans M. Giovannella, G. Mitjia, C. Gregori Pla, M. Kacprzak, D. Ibanez, G. Ruffini, T. Durduran fNIRS 2016, Paris, October 2016
  • Microvascular cerebral metabolism and blood flow and bispectral index C. Lindner, I. Chocron, A. Sanchez-Guerrero, J. L Hollmann, M. Kacprzak, U. M. Weigel, M. de Nadal, J. Sahuquillo, T. Durduran fNIRS 2016, Paris, October 2016
  • Speckle contrast optical spectroscopy of the adult brain with a novel, compact system T. Dragojevic, J. L. Hollmann, D. Tamborini, M. Buttafaca, J. P. Culver, F. Zappa, D. Turgut fNIRS 2016, Paris, October 2016
  • Using diffuse light and speckle statistics to non-invasively measure blood flow; from theoretical foundations to clinical applications T. Durduran International School on Light Sciences and Technologies, Universidad Internacional Menendez Pelayo, June 2016
  • Early cerebral blood flow response to head-of-bed (hob) manipulation is related to outcome in acute ischemic stroke: a transcranial optical monitoring study R. Delgado-Mederos, C. Gregori-Pla, P. Zirak, I. Blanco, L. Prats-Sanchez, A. Martinez-Domeno, J. Marti-Fabregas, T. Durduran ESO 2016, European Stroke Organization Conference, May 2016
  • A new method utilizing novel single-photon avalanche diode arrays for multi-exposure laser speckle flowmetry T. Dragojevic, D. Bronzi, H. M. Varma, C. P. Valdes, C. Castellvi, A. Tosi, F. Zappa, C. Justicia, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
  • Diffuse optical characterization of the human thyroid C. Lindner, M. Mora, P. Farzam, M. Squarcia, J. Johansson, U. M. Weigel, I. Halperin, F. A. Hanzu, D. Turgut OSA Biomedicals Topicals, Optical Society of America, 2016
  • Latest developments in speckle contrast optical tomography (scot) for deep tissue blood flow imaging T. Dragojevic, J. Hollmann, H. M. Varma, C. Valdes, D. Bronzi, D. Tamborini, F. Villa, A. Tosi, F. Zappa, C. Justicia, J. P. Culver, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
  • Variacions en el flux de la microcirculacio cerebral en pacients amb la sindrome d'apnea-hipopnea obstructiva del son (sahs) M. Mayos, C. Gregori-Pla, P. Zirak, I. Blanco, A. Fortuna, G. Cotta, A. Mola, D. Turgut Societat Catalana de Pneumologia, SOCAP, Reus, Spain, April 2016
  • Concurrent diffuse optical measurement of cerebral hemodynamics and eeg during transcranial direct current stimulation (tdcs) in humans M. Giovannella, G. Mitja, C. Gregori-Pla, D. Ibanez, G. Ruffini, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
  • Diffuse optical characterization of the human thyroid C. Lindner, M. Mora, P. Farzam, M. Squarcia, J. Johansson, U. M. Weigel, I. Halperin, F. A. Hanzu, D. Turgut OSA Biomedicals Topicals, Optical Society of America, 2016
  • Long-lasting, liquid phantom for diffuse optical and correlation spectroscopies M. Pagliazzi, M. Giovannella, U. Weigel, A. Pifferi, A. Torricelli, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
  • Non-contact, scanning hyperspectral diffuse optical spectroscopy and diffuse correlation spectroscopy system M. Mireles, J. Johansson, J. Morales-Dalmau, P. Farzam, M. Martinez-Lozano, O. Casanovas, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
  • Simultaneous, non-invasive measurement of local tissue hemodynamics, oxygen metabolism and gold nanorod concentration in vivo J. Morales-Dalmau, M. Mireles, J. Johansson, M. Martinez-Lozano, C. Vilches, V. Sanz, O. Casanovas, R. Quidant, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
  • The babylux project - an optical neuro-monitor of cerebral oxygen metabolism and blood flow for neonatology U. M. Weigel, B. Andresen, V. Chamizo, D. Contini, A. de Carli, R. Donat, T. Durduran, R. Erdmann, M. Fumagalli, M. Giovannella, G. Greisen, S. Hyttel-Sorensen, N. Konig, K. Lauritsen, M. Pagliazzi, A. Pifferi, M. Rehberger, I. Rocchetti, T. Rohlicke, L. Spinelli, M. Wahl, A. Torricelli OSA Biomedicals Topicals, Optical Society of America, 2016
  • Blood flow response to orthostatic challenges in health and diseased populations D. R. Busch, C. Gregori-Pla, I. Blanco, M. Giovannella, C. Favilla, J. Lynch, M. Winters, K. Mensah-Brown, T. Ko, A. McCarthy, J. A. Detre, A. G. Yodh, D. Licht, R. Mesquita, T. Durduran Clinical and Translational Biophotonics 2016, Florida United States, April 2016
  • Cerebral hemodynamic response to an orthostatic challenge in patients with severe obstructive sleep apnea before and after two years of continuous positive air pressure treatment C. Gregori Pla, I. Blanco, P. Zirak, M. Giovannella, A. Fortuna, A. Mola, G. Cotta, M. Mayos, I. Serra, T. Durduran Clinical and Translational Biophotonics 2016, Florida United States, April 2016
  • Characterization of cerebral hemodynamics during obstructive sleep apnea by diffuse optics C. Gregori Pla, P. Zirak, I. Blanco, P. Bramon, A. Fortuna, A. Mola, G. Cotta, M. Mayos, I. Serra, T. Durduran Optics and the Brain 2016, Florida United States, Abril 2016
  • Development and applications of diffuse correlation spectroscopy for non-invasive measurement of blood flow in clinics T. Durduran Optical Tomography and Spectroscopy 2016, Fort Lauderdale, Florida United States, April 2016
  • Diffuse correlation spectroscopy and tomography for longitudinal monitoring of blood flow changes induced by chemotherapy in breast cancer xenografts R. Choe, G. Ramirez, A. R. Proctor, S. Han, T. Durduran, E. B. Brown Cancer Imaging and Therapy 2016, Fort Lauderdale, Florida, United States, April 2016
  • In vivo time domain broadband (600 -1200 nm) diffuse optical characterization of human bone S. Konugolu V. Sekar, A. Dalla Mora, E. Martinenghi, P. Taroni, A. Pifferi, A. Farina, J. Puig, E. Negredo, C. Lindner, M. Pagliazzi, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
  • Measurement of haemodynamics of exercising and non-exercising vastus lateralis muscle with hybrid diffuse optics M. Giovannella, E. Urtane, V. Chamizo, L. Spinelli, R. Re, U. Weigel, Z. Marcinkevics,. T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
  • Variaciones en el flujo de la microcirculación cerebral en pacientes con sí­ndrome de apnea-hipopnea obstructiva del sueño (sahs) M. Mayos, C. Gregori-Pla, P. Zirak, I. Blanco, A. Fortuna, G. Cotta, A. Mola, D. Turgut SEPAR 2016. Sociedad española de pneumologí­a y cirugí­a torácica, 2016
    PhD Theses
  • Translation on non-invasive optical measurements of hemodynamics and oxygen metabolism to the clinic C. Lindner
  • Diffuse optical monitoring of cerebral hemodynamics in experimental and clinical neurology I. Blanco
  • New laser speckle methods for in vivo blood flow imaging and monitoring C. P. Valdés Escobar
  • Hybrid dissuse optics for monitoring of tissue hemodynamics with applications in oncology P. Farzam

Medical Optics

Prof. Dr. Turgut Durduran