Medical Optics

Prof. Dr. Turgut Durduran

Activities:

ICFO-Medical Optics (ICFO-MEDOPT) group was founded in 2009 by Dr Turgut Durduran as an inter-disciplinary group that develops new technologies using advanced photonics for pre-clinical and clinical bio-medicine.

The group’s main expertise is in diffuse optical monitoring and tomography which uses photon diffusion to probe “deep” (0.1-10cm) into tissues. Our research aims to advance the field in theoretical instrumentation and application oriented approaches in parallel. We focus on applications in neurology and oncology and in both pre-clinical animal model studies and in clinical human studies.

Inter-disciplinary, collaborative work forms the core of our vision and we routinely work with biomedical centers, hospitals and engineering departments in Spain, around Europe and abroad. In particular, we have strong ties with other centers in Barcelona area and with researchers at the University of Pennsylvania, USA.

Position(s) Available:
• Research engineer of digital electronics for biomedical optics
• Research engineer position in biomedical optical devices
• Post-doctoral position for novel, new diffuse optical instrumentation
• Post-doctoral position in near-infrared diffuse optical neuromonitoring in the clinics

Research Topics:
• Diffuse Optical Instrumentation For Translational And Clinical Biomedical Research
• Transcranial, Non-invasive Neuro-monitoring With Diffuse Optics
• Translational Stroke Research
• Translational Oncology Research
• Physics Of Photon Migration In Live Tissues

Collaborations:

Links:
• Laser and Ultrasound Co-analyzer for Thyroid Nodules (LUCA)
• Babylux website
• BioNano Science Program @ ICFO

Contact: This email address is being protected from spambots. You need JavaScript enabled to view it.

Medical Optics

Prof. Dr. Turgut Durduran

Group Leader
• Prof. Dr. Turgut Durduran

Postdoctoral Researchers
• Dr. Lorenzo Cortese
• Dr. Giuseppe Lo Presti
• Dr. Manish Verma
• Dr. Ernesto Vidal Rosas

Research Engineers
• Daniel Fernández Cuenca
• Ameer Ghouse

PhD Students
• Stella Avtzi
• Tanja Dragojević
• Pablo Fernández Esteberena
• Jonas Fischer
• Martina Giovannella
• Clara Gregori Pla
• Lisa Kobayashi Frisk
• Jordi Morales Dalmau
• Marco Pagliazzi
• Susanna Tagliabue

Undergrad & Postgrad Students
• Laura Moreno
• Alba Torras

Visiting Scientists
• Dr. Gemma Bale
• Dr. Aykut Eken

Visiting PhD Students
• Federica Maruccia

Former Group Members
• Juan Aguirre, Postdoctoral researcher
• Rubén Benet, Research engineer
• Igor Blanco, PhD student
• Edén Corrales, Research engineer
• Gianluca Cotta, Research engineer
• Parisa Farzam, PhD student
• Alexia Giannoula, Postdoctoral researcher
• Michal Kacprzak, Postdoctoral researcher
• Joseph Hollmann, Postdoctoral researcher
• Johannes Johansson, Research fellow
• Anna Kristoffersen, Postdoctoral researcher
• Martin Leahy, Visiting professor
• Claus Lindner, PhD student
• Taisuke Minagawa, Postdoctoral researcher
• Miguel Mireles, PhD student
• Néstor Oliverio, Research engineer
• Francisco Remiro, Research engineer
• Kristian Sexton, Postdoctoral researcher
• Efraín Solarte, Visiting professor
• Mehmet Ali Süzen, Postdoctoral researcher
• Claudia Patricia Valdés, PhD student
• Hari Varma, Research fellow
• Udo Weigel, Research fellow
• Peyman Zirak, Research fellow
• Iratxe Zuazo, Research engineer

Medical Optics

Prof. Dr. Turgut Durduran

Regular Papers
• Early microvascular cerebral blood flow response to head-of-bed elevation is related to outcome in acute ischemic stroke C. Gregori-Pla, I. Blanco, P. Camps-Renom, P. Zirak, I. Serra, G. Cotta, F. Maruccia, L. Prats-Sánchez, A. Martínez-Domeño, D. R. Busch, G. Giacalone, J. Martí-Fàbregas, T. Durduran, R. Delgado-Mederos J. Neurol. [Online DOI: 10.1007/s00415-019-09226-y] (2019)
• High-resolution mapping of infraslow cortical brain activity enabled by graphene microtransistors E. Masvidal-Codina [et al.] Nature Mat. 18, 280-288 (2018)
• Characterization of the microvascular cerebral blood flow response to obstructive apneic events during night sleep P. Zirak, C. Gregori-Pla, I. Blanco, A. Fortuna, G. Cotta, P. Bramon, I. Serra, A. Mola, J. Solà-Soler, B. F. Giraldo-Giraldo, T. Durduran, M. Mayos Neurophoton. 5, 1 (2018)
• Broadband (550–1350nm) diffuse optical characterization of thyroid chromophores S. Konugolu Venkata Sekar, A. Farina, A. Dalla Mora, C. Lindner, M. Pagliazzi, M. Mora, G. Aranda, H. Dehghani, T. Durduran, P. Taroni, A. Pifferi Sci. Rep. 8, 10015 (2018)
• In vivo time-gated diffuse correlation spectroscopy at quasi-null source-detector separation M. Pagliazzi, S. K. V. Sekar, L. Di Sieno, L. Colombo, T. Durduran, D. Contini, A. Torricelli, A. Pifferi, A. D. Mora Opt. Lett. 43, 2450 (2018) Highlighted in Optics Letters
• Liquid phantoms for near-infrared and diffuse correlation spectroscopies with tunable optical and dynamic properties L. Cortese, G. L. Presti, M. Pagliazzi, D. Contini, A. D. Mora, A. Pifferi, S. K. V. Sekar, L. Spinelli, P. Taroni, M. Zanoletti, U. M. Weigel, S. de Fraguier, A. Nguyen-Dihn, B. Rosinski, T. Durduran Biomed. Opt. Express 9, 2068-2080 (2018)
• Cerebral vasoreactivity in response to a head-of-bed position change is altered in patients with moderate and severe obstructive sleep apnea C. Gregori-Pla, G. Cotta, I. Blanco, P. Zirak, M. Giovannella, A. Mola, A. Fortuna, T. Durduran, M. Mayos PLoS ONE 13, e0194204 (2018)
• Transcranial diffuse optical assessment of the microvascular reperfusion after thrombolysis for acute ischemic stroke R. Delgado-Mederos, C. Gregori Pla, P. Zirak, I. Blanco, L. Dinia, R. Marín, T. Durduran, J. Martí-Fàbregas Biomed. Opt. Express 9, 1262-1271 (2018)
• Diffuse correlation tomography in the transport regime: A theoretical study of the sensitivity to Brownian motion U. Tricoli, C. M. Macdonald, T. Durduran, A. Da Silva, V. A. Markel Phys. Rev. E 97, 022408 (2018)
• Concurrent measurement of cerebral hemodynamics and electroencephalography during transcranial direct current stimulation M. Giovannella, D. Ibañez, C. Gregori-Pla, M. Kacprzak, G. Mitjà, G. Ruffini, T. Durduran Neurophoton. 5, 015001 (2018)
• Compact, multi-exposure speckle contrast optical spectroscopy (SCOS) device for measuring deep tissue blood flow T. Dragojevic, J. L. Hollmann, D. Tamborini, D. Portaluppi, M. Buttafava, J. P. Culver, F. Villa, T. Durduran Biomed. Opt. Express 9, 322 (2018)
• Time-resolved near infrared light propagation using frequency domain superposition S. Wojtkiewicz, T. Durduran, H. Dehghani Biomed. Opt. Express 9, 41 (2018)
• Longitudinal, transcranial measurement of functional activation in the rat brain by diffuse correlation spectroscopy I. Blanco, P. Zirak, T. Dragojevic, C. Castellvi, T. Durduran, C. Justicia Neurophoton. 4, 045006 (2017)
• Time-domain functional diffuse optical tomography system based on fiber-free silicon photomultipliers A. Farina, S. Tagliabue, L. Di Sieno, E. Martinenghi, T. Durduran, S. Arridge, F. Martelli, A. Torricelli, A. Pifferi, A. Dalla Mora Appl. Sci. 7, 1235 (2017)
• Time domain diffuse correlation spectroscopy with a high coherence pulsed source: in vivo and phantom results M. Pagliazzi, S. K. V. Sekar, L. Colombo, E. Martinenghi, J. Minnema, R. Erdmann, D. Contini, A. D. Mora, A. Torricelli, A. Pifferi, T. Durduran Biomed. Opt. Express 8, 5311 (2017)
• Depth sensitivity of frequency domain optical measurements in diffusive media T. Binzoni, A. Sassaroli, A. Torricelli, L. Spinelli, A. Farina, T. Durduran, S. Cavalieri, A. Pifferi, F. Martelli Biomed. Opt. Express 8, 2990-3004 (2017)
• Pre-clinical longitudinal monitoring of hemodynamic response to anti-vascular chemotherapy by hybrid diffuse optics P. Farzam, J. Johansson, M.Mireles, G. Jiménez-Valerio, M. Martínez-Lozano, R. Choe, O. Casanovas, T. Durduran Biomed. Opt. Express 8, 2563 (2017)
• High-density speckle contrast optical tomography (SCOT) for three dimensional tomographic imaging of the small animal brain T. Dragojevi, H. M. Varma, J. L. Hollmann, C. P. Valdes, J. P. Culver, C. Justicia, T. Durduran NeuroImage 153, 283-292 (2017)
• In vivo, non-invasive characterization of human bone by hybrid broadband (600-1200 nm) diffuse optical and correlation spectroscopies S. K. V. Sekar, M. Pagliazzi, E. Negredo, F. Martelli, A. Farina, A. Dalla Mora, C. Lindner, P. Farzam, N. Pérez-Álvarez, J. Puig, P. Taroni, A. Pifferi, T. Durduran PLoS ONE 11, e0168426 (2016)
• Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy G. Ramirez, A. R. Proctor, K. W. Jung, T. T. Wu, S. Han, R. R. Adams, J. Ren, D. K. Byun, K. S. Madden, E. B. Brown, T. H. Foster, P. Farzam, T. Durduran, R. Choe Biomed. Opt. Express 7, 3610 (2016)
• Diffuse optical characterization of the healthy human thyroid tissue and two pathological case studies C. Lindner , M. Mora, P. Farzam, M. Squarcia , J. Johansson, U. M. Weigel, I. Halperin, F. A. Hanzu, T. Durduran PLoS ONE 11, e0147851 (2016)
• Scanning, non-contact, hybrid broadband diffuse optical spectroscopy and diffuse correlation spectroscopy system J. D. Johansson, M. Mireles, J. Morales-Dalmau, P. Farzam, M. Martínez-Lozano, O. Casanovas, T. Durduran Biomed. Opt. Express 6, 481-498 (2016)
• Broadband (600-1350 nm) time resolved diffuse optical spectrometer for clinical use S. Konugolu V. Sekar, A. D. Mora, I. Bargigia, E. Martinenghi, C. Lindner, P. Farzam, M. Pagliazzi, T. Durduran, P. Taroni, A. Pifferi, A. Farina IEEE J. Sel. Top. Quantum Electron. [online10.1109/JSTQE.2015.2506613] (2015)
• Calibration of diffuse correlation spectroscopy blood flow index with venous-occlusion diffuse optical spectroscopy in skeletal muscle Z. Li, W. B. Baker, A. B. Parthasarathy, T. S. Ko, D. Wang, S. Schenkel, T. Durduran, G. Li, A. G. Yodh J. Biomed. Opt. 20, 125005 (2015)
• Pressure modulation algorithm to separate cerebral hemodynamic signals from extracerebral artifacts W. B. Baker, A. B. Parthasarathy, T. S. Ko, D. R. Busch, K. Abramson, S.-Y. Tzeng, R. C. Mesquita,
  T. Durduran, J. H. Greenberg, D. K. Kung, A. G. Yodh Neurophoton. 2, 035004 (2015)
• High-speed multi-exposure laser speckle contrast imaging with a single-photon counting camera T. Dragojević, D. Bronzi, H. M. Varma, C. P. Valdes, C. Castellvi, F. Villa, A. Tosi, C. Justicia, F. Zappa, T. Durduran Biomed. Opt. Express 6, 2865-2876 (2015)
• Non-contact scanning diffuse correlation tomography system for three-dimensional blood flow imaging in a murine bone graft model S. Han, J. Johansson, M. Mireles, A. R. Proctor, M. D. Hoffman, J. B. Vella, D. S. W. Benoit, T. Durduran, R. Choe Biomed. Opt. Express 6, 2695-2712 (2015)
• Fast silicon photomultiplier improves signal harvesting and reduces complexity in time-domain diffuse optics A. Dalla Mora, E. Martinenghi, D. Contini, A. Tosi, G. Boso, T. Durduran, S. Arridge, F. Martelli, A. Farina, A. Torricelli, A. Pifferi Opt. Express 23, 13937-13946 (2015) Highlighted in LaserFocusWorld, OSA, and VJBO
• Multidistance diffuse correlation spectroscopy for simultaneous estimation of blood flow index and optical properties P. Farzam, T. Durduran J. Biomed. Opt. 20, 055001 (2015)
• Towards next-generation time-domain diffuse optics for extreme depth penetration and sensitivity A. D. Mora, D. Contini, S. Arridge, F. Martelli, A. Tosi, G. Boso, A. Farina, T. Durduran, E. Martinenghi, A. Torricelli, A. Pifferi Biomed. Opt. Express 6, 1749-1760 (2015)
• Hardware simulator for optical correlation spectroscopy with Gaussian statistics and arbitrary correlation functions M. Molteni, U. M. Weigel, F. Remiro, T. Durduran, F. Ferri Opt. Express 22, 28002-28018 (2014)
• The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures J. Aguirre, J. Morales-Dalmau, L. Funk, F. Jara, P. Turon, T. Durduran Biomed. Opt. Express 5, 2856-2869 (2014)
• Speckle contrast optical spectroscopy, a non-invasive, diffuse optical method for measuring microvascular blood flow in tissue C. P. Valdes, H. M. Varma, A. K. Kristoffersen, T. Dragojevic, J. P. Culver, T. Durduran Biomed. Opt. Express 5, 2769-2784 (2014)
• Optically measured microvascular blood flow contrast of malignant breast tumors R. Choe, M. E. Putt, P. M. Carlile, T. Durduran, J. M. Giammarco, D. R. Busch, K W. Jung, B. J. Czerniecki, J. Tchou, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, A. DeMichele, A. G. Yodh PLoS ONE 9, e99683 (2014)
• Noninvasive characterization of the healthy human manubrium using diffuse optical spectroscopies P. Farzam, C. Lindner, U. M. Weigel, M. Suarez, A. Urbano-Ispizua, T. Durduran Physiol. Meas. 35, 1469-1491 (2014)
• Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink L. Spinelli, M. Botwicz, N. Zolek, M. Kacprzak, D. Milej, P. Sawosz, A. Liebert, U. Weigel, T. Durduran, F. Foschum, A. Kienle, F. Baribeau, S. Leclair, J.-P. Bouchard, I. Noiseux, P. Gallant, O. Mermut, A. Farina, A. Pifferi, A. Torricelli,
  R. Cubeddu, H.-C. Ho, M. Mazurenka, H. Wabnitz, K. Klauenberg, O. Bodnar, C. Elster, M. Bénazech-Lavoué, Y. Bérubé-Lauzière, F. Lesage, D. Khoptyar, A. A. Subash, S. Andersson-Engels, P. Di Ninni, F. Martelli, G. Zaccanti Biomed. Opt. Express 5, 2037-2053 (2014)
• Mannose-binding lectin promotes local microvascular thrombosis after transient brain ischemia in mice X. de la Rosa, A. Cervera, A. K. Kristoffersen, C. P. Valdés, H. M. Varma, C. Justicia, T. Durduran,
  A. Chamorro, A. M. Planas Stroke [Online DOI: 10.1161/​STROKEAHA.113.004111] (2014)
• Speckle contrast optical tomography: A new method for deep tissue three-dimensional tomography of blood flow H. M. Varma, C. P. Valdes, A. K. Kristoffersen, J. P. Culver, T. Durduran Biomed. Opt. Express 5, 1275-1289 (2014)
• Optical bedside monitoring of cerebral blood flow in acute ischemic stroke patients during head-of-bed manipulation C. G. Favilla, R. C. Mesquita, M. Mullen, T. Durduran, X. Lu, M. N. Kim, D. L. Minkoff, S. E. Kasner, J. H. Greenberg,
  A. G. Yodh, J. A. Detre Stroke [Online DOI: 10.1161/​STROKEAHA.113.004116] (2014) Highlighted in Penn Medicine
• Microvascular versus macrovascular cerebral vasomotor reactivity in patients with severe internal carotid artery stenosis or occlusion P. Zirak, R. Delgado-Mederos, L. Dinia, J. Martí-Fàbregas, T. Durduran Acad. Radiol. 21, 168-174 (2014)
• Blood flow reduction in breast tissue due to mammographic compression D. R. Busch, R. Choe, T. Durduran, D. H. Friedmand, W. B. Baker, A. D. Maidment, M. A. Rosen,
  M. D. Schnall, A. G. Yodh Acad. Radiol. 21, 151-156 (2014)
• Transcranial diffuse optical monitoring of microvascular cerebral hemodynamics after thrombolysis in ischemic stroke P. Zirak, R. Delgado-Mederos, L. Dinia, D. Carrera, J. Martí-Fàbregas, T. Durduran J. Biomed. Opt. 19, 018002 (2014)
• Diffuse correlation spectroscopy for non-invasive, micro-vascular cerebral blood flow measurement T. Durduran, A. G. Yodh NeuroImage 85, 51-63 (2014)
• A low memory cost model based reconstruction algorithm exploiting translational symmetry for photoacustic microscopy J. Aguirre, A. Giannoula, T. Minagawa, L. Funk, P. Turon, T. Durduran Biomed. Opt. Express 4, 2813-2827 (2013)
• Pulsatile and steady-state hemodynamics of the human patella bone by diffuse optical spectroscopy P. Farzam, P. Zirak, T. Binzoni, T. Durduran Physiol. Meas. 34, 839-857 (2013) Highlighted in Physiol. Meas.
• Toward noninvasive characterization of breast cancer and cancer metabolism with diffuse optics D. R. Busch, R. Choe, T. Durduran, A. G. Yodh PET Clin. 8, 345-365 (2013)
• Continuous optical monitoring of cerebral hemodynamics during head-of-bed manipulation in brain-injured adults M. N. Kim, B. L. Edlow, T. Durduran, S. Frangos, R. C. Mesquita, J. M. Levine, J. H. Greenberg, A. G. Yodh, J. A. Detre Neurocrit. Care 20, 443-453 (2013)
• Diffuse optical characterization of an exercising patient group with peripheral artery disease R. C. Mesquita, M. Putt, M. Chandra, G. Yu, X. Xing, S. W. Han, G. Lech, Y. Shang, T. Durduran, C. Zhou,
  A. G. Yodh, E. R. Mohler J. Biomed. Opt. 18, 057007 (2013)
• Sodium bicarbonate causes dose-dependent increases in cerebral blood flow in infants and children with single ventricle physiology E. M. Buckley, M. Y. Naim, J. M. Lynch, D. A. Goff, P. J. Schwab, L. K. Diaz, S. C. Nicolson, L. M. Montenegro,
  N. A. Lavin, T. Durduran, T. L. Spray, J. W. Gaynor, M. E. Putt, A. G. Yodh, M. A. Fogel, D. J. Licht Pediatr. Res. 73, 668-673 (2013)
• Early postoperative changes in cerebral oxygen metabolism following neonatal cardiac surgery: Effects of surgical duration E. M. Buckley, J. M. Lynch, D. A. Goff, P. J. Schwab, W. B. Baker, T. Durduran, D. R. Busch, S. C. Nicolson,
  L. M. Montenegro, M. Y. Naim, R. Xiao, T. L. Spray, A. G. Yodh, J. W. Gaynor, D. J. Licht J. Thorac. Cardiovasc. Surg. 145, 196-205 (2013)
• Neurovascular coupling varies with level of global cerebral ischemia in a rat model W. B. Baker, Z. Sun, T. Hiraki, M. E. Putt, T. Durduran, M. Reivich, A. G. Yodh, J. H. Greenberg J. Cerebr. Blood F. Met. 33, 97-105 (2013)
• Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy D. R. Busch, R. Choe, M. A. Rosen, W. Guo, T. Durduran, M. D. Feldman, C. Mies, B. J. Czerniecki, J. Tchou,
  A. DeMichele, M. D. Schnall, A. G. Yodh Biomed. Opt. Express 4, 105-121 (2013)
• Low-cost diffuse optical tomography for the classroom T. Minagawa, P. Zirak, U. M. Weigel, A. K. Kristoffersen, N. Mateos, A. Valencia, T. Durduran Am. J. Phys. 80, 876-881 (2012)
• Diffuse optical monitoring of the neoadjuvant breast cancer therapy R. Choe, T. Durduran IEEE J. Sel. Top. Quantum Electron. 18, 1367-1386 (2012) Invited paper
• Validation of diffuse correlation spectroscopic measurement of cerebral blood flow using phase-encoded velocity mapping magnetic resonance imaging E. M. Buckley, D. Hance, T. Pawlowski, J. Lynch, F. B. Wilson, R. C. Mesquita, T. Durduran, L. K. Diaz,
  M. E. Putt, D. J. Licht, M. A. Fogel, A. G. Yodh J. Biomed. Opt. 17, 037007 (2012)
• Direct measurement of tissue blood flow and metabolism with diffuse optics R. C. Mesquita, T. Durduran, G. Yu, E. M. Buckley, M. N. Kim, C. Zhou, R. Choe, U. Sunar, A. G. Yodh Phil. Trans. R. Soc. A 369, 4390-4406 (2011)
• Effects of acetazolamide on the micro- and macro-vascular cerebral hemodynamics: a diffuse optical and transcranial doppler ultrasound study P. Zirak, R. Delgado-Mederos, J. Martí-Fàbregas, T. Durduran Biomed. Opt. Express 1, 1443-1459 (2010) Highlighted in Spotlight of Optics
• Compressed sensing in diffuse optical tomography M. Süzen, A. Giannoula, T. Durduran Opt. Express 18, 23676-23690 (2010) Highlighted in Virt. J. Biological Phys. Research
  Highlighted in Virt. J. Biomedical Opt.
• Effects of muscle fiber motion on diffuse correlation spectroscopy blood flow measurements during exercise Y. Shang, T. B. Symons, T. Durduran, A. G. Yodh, G. Yu Biomed. Opt. Express 1, 500-511 (2010)
• The biological effect of contralateral forepaw stimulation in rat focal cerebral ischemia: a multispectral optical imaging study J. Luckl, W. Baker, Z.-H. Sun, T. Durduran, A. G. Yodh, J. H. Greenberg Front. Neuroenerg. 2, 19 (2010)
• Diffuse optics for tissue monitoring and tomography T. Durduran, R. Choe, W. B. Baker, A. G. Yodh Rep. Prog. Phys. 73, 076701 (2010)
• Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with heart defects T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, J. W. Gaynor, T. L. Spray, S. M. Durning,
  S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, D. J. Licht J. Biomed. Opt. 15, 037004 (2010)
• Computer aided automatic detection of malignant lesions in diffuse optical mammography D. R. Buscha, W. Guo, R. Choe, T. Durduran, M. D. Feldman, C. Mies, M. A. Rosen, M. D. Schnall, B. J. Czerniecki, J. Tchou, A. DeMichele, M. E. Putt, A. G. Yodh Med. Phys. 37, 1840-1844 (2010)
• Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults M. N. Kim , T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, W. A. Kofke Neurocrit. Care 12, 173-180 (2010) Link to Neurocrit. Care
• The effects of healthy aging on cerebral hemodynamic responses to posture change B. L. Edlow, M. N. Kim, T. Durduran, C. Zhou, M. E. Putt, A. G. Yodh, J. H. Greenberg, J. A. Detre Physiol. Meas. 31, 477-495 (2010)
• Noninvasive cerebral perfusion imaging in high risk neonates D. Goff, E. Buckley, T. Durduran, J. J. Wang, D. J. Licht Semin. Perinatol. 34, 46-56 (2010)
• Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound E. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht,
  P. H. Arger, M. E. Putt, H. H. Hurt, A. G. Yodh Opt. Express 17, 12571-12581 (2009) Highlighted in Virtual Journal for Biomedical Optics
• Epidermal growth factor receptor inhibition modulates the microenvironment by vascular normalization to improve chemotherapy and radiotherapy efficacy G. J. Cerniglia, N Pore, J. H. Tsai, S. Schultz, R. Mick, R. Choe, X. Xing, T. Durduran, A. G. Yodh, S. M. Evans,
  C. J. Koch, S. M. Hahn, H. Quon, C. M. Sehgal, W. M. F. Lee, A. Maity PLoS ONE 4, e6539 (2009)
• Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, A. G. Yodh J. Biomed. Opt. 14, 034015 (2009) Link to J. Biomed. Opt.
• Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner,
  J. H. Greenberg, A. G. Yodh, J. A. Detre Opt. Express 17, 3884-3902 (2009) Highlighted in The Virtual Journal for Biomedical Optics
• Characterization of periinfarct flow transients with laser speckle and doppler after middle cerebral artery occlusion in the rat J. Luckl, C. Zhou, T. Durduran, A.G. Yodh, J.H. Greenberg J. Neurosci. Res. 87, 1219-1229 (2009) Link to J. Neurosci. Res.
• Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography R. Choe, S. D. Konecky, A. Corlu, K. Lee, T. Durduran, D. R. Busch, S. Pathak, B. J. Czerniecki, J. Tchou, D. L. Fraker, A. DeMichele, B. Chance, S. R. Arridge, M. Schweiger, J. P. Culver, M. D. Schnall, M. E. Putt, M. A. Rosen, A. G. Yodh J. Biomed. Opt. 14, 024020 (2009) Link to J. Biomed. Opt.

Invited Talks
• Non-invasive, diffuse optical techniques for functional imaging T. Durduran VIII Spanish Drug Discovery Network Meeting 2016, volume Invited talk. SLAS Europe, November 2016
• Non-invasive, diffuse optical techniques for functional imaging T. Durduran VIII Spanish Drug Discovery Network Meeting 2016, SLAS Europe, November 2016
• Hybrid near-infrared diffuse optical methods for bed-side cerebral monitoring T. Durduran XVII Simposium Internacional de Neuromonitorizacion y Tratamiento Del Paciente Neurocritico (PIC 2016), Barcelona, November 2016.
• Measuring cerebral blood flow with diffuse correlation spectroscopy J. Hollmann, T. Durduran 3rd European autumn school on cerebral oxymetry and optical imaging. University of Picardie, Amiens, November 2016.
• Non-invasive, diffuse optical techniques for functional imaging T. Durduran VIII Spanish Drug Discovery Network Meeting 2016, SLAS Europe, November 2016
• 'Why is my hand red?' or the tales of diffuse light in tissues T. Durduran Jornadas de Estudiantes en Ingenieria Biomedica, IEEE EMBS BCN Student Club, July 2016
• Using light to probe inside the body T. Durduran Pint of Science Festival 2016, Barcelona, May 2016
• Development and applications of diffuse correlation spectroscopy for non-invasive measurement of blood flow in clinics T. Durduran Optical Tomography and Spectroscopy 2016, Fort Lauderdale, Florida United States, April 2016
• Cerebral metabolism and blood flow during bispectral index-controlled, propofol-induced anesthesia assessed by hybrid diffuse optics C. Lindner, I. Chochrón da Prat, Á. Sánchez-Guerrero, U. M. Weigel, M. de Nadal, J. Sahuquillo, D. Turgut OSA Biomedicals Topicals, Optical Society of America, 2016
• High density speckle contrast optical tomography for transcranial, three-dimensional imaging of cerebral blood flow in rodents J. Hollmann, T. Dragojevi?, H. M. Varma, C. Justicia, C. Valdes, J. P. Culver, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
• How can you see inside my body with light? T. Durduran 4th Symposium of Update in Dialysis, Hospital Clinic Barcelona, April 2016
• Hybrid near-infrared diffuse optical methods for bed-side cerebral monitoring T. Durduran 9th International Update on Neuro-Anesthesia & Neuro-intensive care, Hospital Clinic Barcelona, April 2016
• Hybrid near-infrared diffuse optical methods for bed-side cerebral monitoring T. Durduran 9th International Update on Neuro-Anesthesia & Neuro-intensive Care, Barcelona, April 2016

Talks
• Photonics advancements in time-domain diffuse imaging: Towards hand-held and wearable devices A. Pifferi, A. Dalla Mora, E. Martinenghi, D. Contini, L. di Sieno, R. Re, S. Arridge, F. Martelli, A. Tosi, A. Farina, T. Durduran,. A. Torricelli Optical Tomography and Spectroscopy 2016, Fort Lauderdale, Florida United States, April 2016
• Neuromonitoring and imaging of cerebral blood flow with diffuse correlation spectroscopy T. Durduran University of Picardie Jules Verne and the Faculty of Medecine, November 2016
• Neuromonitoring and imaging of cerebral blood flow with diffuse correlation spectroscopy T. Durduran 4th European autumn school on cerebral oxymetry and optical imaging. University of Picardie, Amiens, November 2016
• Compact eight channel time-domain diffuse optical tomography system based on SiPMs for functional brain imaging S. Tagliabue, L. Di Sieno, A. Dalla Mora, E. Martinenghi, A. Farina, D. Turgut, A. Torricelli, A. Pifferi fNIRS 2016, Paris, France, October 2016
• Concurrent diffuse optical measurement of cerebral hemodynamics and EEG during transcranial direct current stimulation (tDCS) in humans M. Giovannella, G. Mitjia, C. Gregori Pla, M. Kacprzak, D. Ibanez, G. Ruffini, T. Durduran fNIRS 2016, Paris, October 2016
• Microvascular cerebral metabolism and blood flow and bispectral index C. Lindner, I. Chocron, A. Sanchez-Guerrero, J. L Hollmann, M. Kacprzak, U. M. Weigel, M. de Nadal, J. Sahuquillo, T. Durduran fNIRS 2016, Paris, October 2016
• Speckle contrast optical spectroscopy of the adult brain with a novel, compact system T. Dragojevic, J. L. Hollmann, D. Tamborini, M. Buttafaca, J. P. Culver, F. Zappa, D. Turgut fNIRS 2016, Paris, October 2016
• Using diffuse light and speckle statistics to non-invasively measure blood flow; from theoretical foundations to clinical applications T. Durduran International School on Light Sciences and Technologies, Universidad Internacional Menendez Pelayo, June 2016
• Early cerebral blood flow response to head-of-bed (hob) manipulation is related to outcome in acute ischemic stroke: a transcranial optical monitoring study R. Delgado-Mederos, C. Gregori-Pla, P. Zirak, I. Blanco, L. Prats-Sanchez, A. Martinez-Domeno, J. Marti-Fabregas, T. Durduran ESO 2016, European Stroke Organization Conference, May 2016
• A new method utilizing novel single-photon avalanche diode arrays for multi-exposure laser speckle flowmetry T. Dragojevic, D. Bronzi, H. M. Varma, C. P. Valdes, C. Castellvi, A. Tosi, F. Zappa, C. Justicia, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
• Diffuse optical characterization of the human thyroid C. Lindner, M. Mora, P. Farzam, M. Squarcia, J. Johansson, U. M. Weigel, I. Halperin, F. A. Hanzu, D. Turgut OSA Biomedicals Topicals, Optical Society of America, 2016
• Latest developments in speckle contrast optical tomography (scot) for deep tissue blood flow imaging T. Dragojevic, J. Hollmann, H. M. Varma, C. Valdes, D. Bronzi, D. Tamborini, F. Villa, A. Tosi, F. Zappa, C. Justicia, J. P. Culver, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
• Variacions en el flux de la microcirculacio cerebral en pacients amb la sindrome d'apnea-hipopnea obstructiva del son (sahs) M. Mayos, C. Gregori-Pla, P. Zirak, I. Blanco, A. Fortuna, G. Cotta, A. Mola, D. Turgut Societat Catalana de Pneumologia, SOCAP, Reus, Spain, April 2016
• Concurrent diffuse optical measurement of cerebral hemodynamics and eeg during transcranial direct current stimulation (tdcs) in humans M. Giovannella, G. Mitja, C. Gregori-Pla, D. Ibanez, G. Ruffini, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
• Diffuse optical characterization of the human thyroid C. Lindner, M. Mora, P. Farzam, M. Squarcia, J. Johansson, U. M. Weigel, I. Halperin, F. A. Hanzu, D. Turgut OSA Biomedicals Topicals, Optical Society of America, 2016
• Long-lasting, liquid phantom for diffuse optical and correlation spectroscopies M. Pagliazzi, M. Giovannella, U. Weigel, A. Pifferi, A. Torricelli, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
• Non-contact, scanning hyperspectral diffuse optical spectroscopy and diffuse correlation spectroscopy system M. Mireles, J. Johansson, J. Morales-Dalmau, P. Farzam, M. Martinez-Lozano, O. Casanovas, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
• Simultaneous, non-invasive measurement of local tissue hemodynamics, oxygen metabolism and gold nanorod concentration in vivo J. Morales-Dalmau, M. Mireles, J. Johansson, M. Martinez-Lozano, C. Vilches, V. Sanz, O. Casanovas, R. Quidant, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
• The babylux project - an optical neuro-monitor of cerebral oxygen metabolism and blood flow for neonatology U. M. Weigel, B. Andresen, V. Chamizo, D. Contini, A. de Carli, R. Donat, T. Durduran, R. Erdmann, M. Fumagalli, M. Giovannella, G. Greisen, S. Hyttel-Sorensen, N. Konig, K. Lauritsen, M. Pagliazzi, A. Pifferi, M. Rehberger, I. Rocchetti, T. Rohlicke, L. Spinelli, M. Wahl, A. Torricelli OSA Biomedicals Topicals, Optical Society of America, 2016
• Blood flow response to orthostatic challenges in health and diseased populations D. R. Busch, C. Gregori-Pla, I. Blanco, M. Giovannella, C. Favilla, J. Lynch, M. Winters, K. Mensah-Brown, T. Ko, A. McCarthy, J. A. Detre, A. G. Yodh, D. Licht, R. Mesquita, T. Durduran Clinical and Translational Biophotonics 2016, Florida United States, April 2016
• Cerebral hemodynamic response to an orthostatic challenge in patients with severe obstructive sleep apnea before and after two years of continuous positive air pressure treatment C. Gregori Pla, I. Blanco, P. Zirak, M. Giovannella, A. Fortuna, A. Mola, G. Cotta, M. Mayos, I. Serra, T. Durduran Clinical and Translational Biophotonics 2016, Florida United States, April 2016
• Characterization of cerebral hemodynamics during obstructive sleep apnea by diffuse optics C. Gregori Pla, P. Zirak, I. Blanco, P. Bramon, A. Fortuna, A. Mola, G. Cotta, M. Mayos, I. Serra, T. Durduran Optics and the Brain 2016, Florida United States, Abril 2016
• Development and applications of diffuse correlation spectroscopy for non-invasive measurement of blood flow in clinics T. Durduran Optical Tomography and Spectroscopy 2016, Fort Lauderdale, Florida United States, April 2016
• Diffuse correlation spectroscopy and tomography for longitudinal monitoring of blood flow changes induced by chemotherapy in breast cancer xenografts R. Choe, G. Ramirez, A. R. Proctor, S. Han, T. Durduran, E. B. Brown Cancer Imaging and Therapy 2016, Fort Lauderdale, Florida, United States, April 2016
• In vivo time domain broadband (600 -1200 nm) diffuse optical characterization of human bone S. Konugolu V. Sekar, A. Dalla Mora, E. Martinenghi, P. Taroni, A. Pifferi, A. Farina, J. Puig, E. Negredo, C. Lindner, M. Pagliazzi, T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
• Measurement of haemodynamics of exercising and non-exercising vastus lateralis muscle with hybrid diffuse optics M. Giovannella, E. Urtane, V. Chamizo, L. Spinelli, R. Re, U. Weigel, Z. Marcinkevics,. T. Durduran OSA Biomedicals Topicals, Optical Society of America, 2016
• Variaciones en el flujo de la microcirculación cerebral en pacientes con sí­ndrome de apnea-hipopnea obstructiva del sueño (sahs) M. Mayos, C. Gregori-Pla, P. Zirak, I. Blanco, A. Fortuna, G. Cotta, A. Mola, D. Turgut SEPAR 2016. Sociedad española de pneumologí­a y cirugí­a torácica, 2016

Seminars
• Bed-side monitoring of cerebral hemodynamics with hybrid diffuse optics T. Durduran BP4L webinar, February 2011

PhD Theses
• Translation on non-invasive optical measurements of hemodynamics and oxygen metabolism to the clinic C. Lindner
• Diffuse optical monitoring of cerebral hemodynamics in experimental and clinical neurology I. Blanco
• New laser speckle methods for in vivo blood flow imaging and monitoring C. P. Valdés Escobar
• Hybrid dissuse optics for monitoring of tissue hemodynamics with applications in oncology P. Farzam

Medical Optics

Prof. Dr. Turgut Durduran

• 2019-02-15 Congratulations to New ICFO PhD graduate Dr. Jordi Morales graduated with the thesis “From Cells to Tissues, Microscopy to Modeling: Towards Precise, Data-Driven Photothermal Therapy with Gold Nanorods”
• 2019-01-02 Graphene-based implant for record brain activity at extremely low frequencies Researchers from ICN2, IMB-CNM, CSIC, IDIBAPS, and ICFO report in Nature Materials a graphene-based implant able to record electrical activity in the brain at extremely low frequencies and over large areas.
• 2018-10-24 Congratulations to New ICFO PhD graduate Dr. Miguel Mireles graduated with a thesis on “Hybrid diffuse optics for translational oncology and nanobiophotonics: Towards a Theranostic Approach for Emerging Cancer Therapies
• 2018-07-19 L4H Seminar
  MAVI SANCHEZ-VIVES \'From bistability to complexity in the cortical network\' MAVI SANCHEZ-VIVES
  IDIBAPS
  
• 2018-06-07 Medical Optics in OSA Editors pick A study reporting new method with for more sensitive, compact and depth resolved, non-invasive blood flow measurement is chosen as part of the OSA Editor’s pick of the week.
• 2018-03-19 Medical Optics for Sleep Apnea ICFO researchers develop a non-invasive, point-of-care optical device to study this sleeping disorder and its treatment.
• 2018-03-12 A non-invasive, bed-side optical device could help reduce Stroke-associated disability Study published in OSA’s Biomedical Optics Express
• 2018-02-06 ICFO at Photonics West 2018 ICREA Professor at ICFO Turgut Durduran invited to give a presentation in the Hot Topics session of the SPIE BiOS conference.
• 2017-07-12 Bringing technological innovations to market The development of an optical medical device carried out by the research group led by ICREA Prof. at ICFO Turgut Durduran receives LLAVOR funding from GenCat.
• 2017-06-27 OSA’s Student Presentation Award ICFO PhD Student Clara Gregori receives award at ECBO
• 2017-06-06 BABYLUX: the light that brightens the lives of premature babies The Babylux project comes to an end with promosing results on diffuse optics monitoring of oxygenation levels and cerebral blood flow in premature babies.
• 2017-05-29 SPIE Optics and Photonics Education Scholarship ICFO PhD student Jordi Morales awarded for potential contribution to the field of optics and photonics
• 2017-04-20 SCOT improves stroke diagnosis New viable and non-invasive 3D method for imaging the small animal brain and quantifying cerebral blood flow.
• 2017-03-24 Congratulations to New ICFO PhD graduate Dr. Claus Lindner graduated with a thesis in “Translation of Non-Invasive Optical Measurements of Hemodynamics and Oxygen Metabolism to the Clinic”
• 2016-11-30 FEDER Funding for Medical Photonics Platform ICFO and Parc Sanitari Pere Virgili to collaborate on non-invasive optical platform for cerebrovascular risk assessment in ageing
• 2016-11-16 GE Lights for Life Challenge Dr. Joseph Hollmann wins 3rd place in contest aiming to intelligently connect lighting to life.
• 2016-03-21 BIONANO @ ICFO ICFO is setting a rapid pace in the advancement of BioNano research
• 2016-03-14 LUCA- Innovative technology for thyroid cancer screening ICFO leads EU project to develop a novel, point-of-care, low-cost device to screen thyroid nodules
• 2016-01-28 New Proof of Concept ERC funding for GRAPHEALTH: graphene wearable technology
• 2016-01-28 Thyroid cancer screening Pioneering research in the application of diffuse optics for precise characterization and diagnosis
• 2015-11-03 ICFO @ GRAPCHINA 2015 From October 28-30th, ICFO participated in the 2nd Edition of the International Graphene Innovation Conference
• 2015-04-01 “la Caixa” Foundation supports development of Photonics for health ICFO leads program for clinical investigation of Photonic platforms for noninvasive measurement of pathological and physiological properties of tissues.
• 2014-10-14 Congratulations to New ICFO PhD graduate Dr. Parisa Farzam graduated with a thesis in ‘Hybrid Diffuse Optics for Monitoring of Tissue Hemodynamics with Applications in Oncology’
• 2014-08-13 Speckle contrast optical spectroscopy A new non-invasive, diffuse optical method for measuring microvascular blood flow in tissue
• 2014-06-03 New Tenured Group Leader Prof. Turgut Durduran awarded tenure at ICFO.
• 2014-04-23 ICFO’s spin-off HEMOPHOTONICS wins European Innovation Award Project wins first runner-up in the SPIE Photonics Innovation Village.
• 2014-01-27 BabyLux European Project ICFO will participate in a multimillion euro project to improve quality of life for critically ill newborns.
• 2014-01-22 ICFO in Special Issue of Academic Radiology Two articles co-authored by ICFO’s Medical Optics Group in Britton Chance 100th Commemorative issue.
• 2013-11-18 Faster Algorithms for Photoacoustic Imaging Microscopy Industrial Collaboration with B. Braun leads to a publication in Biomedical Optics Express
• 2013-07-29 ICFO clinical results highlighted in Physiological Measurement Featured article on measurement of bone hemodynamics by diffuse optics.
• 2012-01-18 Neuro-intensive Care Foundation CERCA funds the pre-commercial prototype development of a project led by Prof. Turgut Durduran.
• 2011-09-19 ICFO & B.Braun Team up The research agreement will explore the opportunities of combining the expertise in their corresponding fields of knowledge.
• 2011-01-18 ICFO in OSA Spotlight A study on cerebral hemodynamics with diffuse optics by ICFO and Hospital de Sant Pau highlighted in OSA’s Spotlight on Optics.
• 2010-06-11 Diffuse Optics Diagnosis Prof. Turgut Durduran and co-authors have published a review on medical applications of diffuse light.
• 2010-05-14 Neonatal Intensive Care ICFO Prof. Turgut Durduran reports new advances in monitoring of neonates with heart conditions.
• 2009-11-09 Photonics 4 Life at ICFO Third Scientific Meeting of Photonics for Life Network of Excellence.
• 2009-05-29 ICFO Highlighted in VJBO Research co-authored by ICFOnians highlighted in the Virtual Journal of Biomedical Optics.
• 2009-05-26 Blue Babies Research by Prof. Turgut Durduran on “blue babies” is reported by the El País newspaper.
• 2009-03-04 Photonics Against Stroke Bedside monitoring of brain blood flow in stroke victims is the outcome of research conducted by Prof. Turgut Durduran, who has recently joined ICFO.
• 2008-12-22 ICFO Welcomes a New Junior Group Leader Dr. Durduran will boost ICFO’s medical photonics program sponsored by the Cellex Foundation.